About The ICE Project
The healthcare sector is resource-intensive and contributes substantially to climate change and its negative health impacts. To build sustainable healthcare systems, randomised trials should assess environmental outcomes, such as climate impact, so that new interventions are evaluated for their effects on both patients and the planet.
The ICE Project brings together international experts to develop extensions to the SPIRIT 2025 and CONSORT 2025 guidelines, guiding the reporting of environmental outcomes in clinical trials.
These new guidelines, SPIRIT-ICE and CONSORT-ICE, will enable trialists to report measures such as carbon footprint, waste, and resource use alongside clinical outcomes. The SPIRIT-ICE and CONSORT-ICE extensions have been registered with the Enhancing the QUAlity and Transparency Of health Research (EQUATOR) Network. The registrations are available here and here.
Our vision is that, in the near future, all major trials will integrate environmental outcomes with clinical ones, benefitting both current and future patients, the public, and the planet.
Organisation
The ICE Steering Group
Johanne Juul Petersen
Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark.
Linn Hemberg
Anesthesiology and Intensive Care, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.
Lund University Agenda 2030 Graduate School, Lund University, Lund, Sweden
Lehana Thabane
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton ON, Canada
Biostatistics Unit, St Joseph’s Healthcare—Hamilton, Hamilton ON, Canada
Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa
Sally Hopewell
Oxford Clinical Trials Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK
An-Wen Chan
Department of Medicine, Women’s College Research Institute, University of Toronto, Toronto, Ontario, Canada
Peter Bentzer
Anesthesiology and Intensive Care, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.
Department of Anaesthesia and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden
Janus Christian Jakobsen
Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark
The ICE Group
Johanne Juul Petersen
Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark.
Linn Hemberg
Anesthesiology and Intensive Care, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.
Lund University Agenda 2030 Graduate School, Lund University, Lund, Sweden
Lehana Thabane
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton ON, Canada
Biostatistics Unit, St Joseph’s Healthcare—Hamilton, Hamilton ON, Canada
Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa
Sally Hopewell
Oxford Clinical Trials Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK
An-Wen Chan
Department of Medicine, Women’s College Research Institute, University of Toronto, Toronto, Ontario, Canada
Asbjørn Hróbjartsson
Cochrane Denmark and Centre for Evidence-Based Medicine Odense (CEBMO), Department of Clinical Research, University of Southern Denmark, Denmark
Open Patient data Explorative Network (OPEN), Odense University Hospital, Denmark
Ole Mathiesen
Department of Anaesthesia, Centre for Anaesthesiological Research, Zealand University Hospital, Køge, Denmark.'
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Sujane Kandasamy
Department of Child & Youth Studies, Brock University
Department of Medicine, Faculty of Health Sciences, McMaster University
Nandi Siegfried
Mental Health, Alcohol, Substance Use and Tobacco Research Unit, South African Medical Research Council, Tygerberg, South Africa
Paula R Williamson
MRC-NIHR Trials Methodology Research Partnership, Department of Health Data Science, University of Liverpool, Liverpool, UK
Lisa Fox
ICR-CTSU, The Institute of Cancer Research, London, UK
Caroline Barkholt Kamp
Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
Jean-Marc Hoffmann
Clinical Trials Center, University of Zurich and University Hospital Zurich, Zurich, Switzerland
Stig Brorson
Centre for Evidence-Based Orthopedics, Zealand University Hospital and Department of Clinical Medicine, University of Copenhagen, Denmark
Isabelle Boutron
Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Centre for Research in Epidemiology and Statistics (CRESS), Paris, France
Centre d’Epidémiologie Clinique, Hôpital Hôtel Dieu, AP-HP, Paris, France
Forbes McGain
Department of Critical Care, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia
Departments of Anaesthesia and Intensive Care Medicine, Western Health, Footscray, Victoria, Australia
School of Public Health, University of Sydney, Sydney, New South Wales, Australia
Scott McAlister
Department of Critical Care, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia
Sydney School of Public Health, University of Sydney, Sydney, New South Wales, Australia
Lilian Mutengu
African Academy of Sciences, Nairobi, Kenya
Jonathan Slutzman
Center for the Environment and Health Massachusetts General Hospital Harvard Medical School
Jodi Sherman
Yale Center on Climate Change and Health Yale School of Public Health
Peter Bentzer
Anesthesiology and Intensive Care, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.
Department of Anaesthesia and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden
Janus Christian Jakobsen
Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark